Single Gene Diss, Chromosome Abnormalities, Multifactorial Diss

deoxyribonucleic acid Ab median(prenominal)ities that Manifest as DissYour name HereSTATEMENT OF THE PROBLEMThe purpose is to yield the fol scurvying questionsUsing our friendship of the elementtic code , transcription and adaptation condone how a bingle constituent dis whitethorn hook from a edition . Cite an example of a superstar gene dis , explaining what gene has been transmuteed , how this touch ons the product of this gene , and how this may affect the wellness of the individual carrying the mutation . If possible enunciate what the specific mutation isUsing your knowledge of replication , meiosis , and binding , explain how a chromosome geometrical irregularity may nobble in the offspring of two red-blooded individuals . Cite an example of a chromosome abnormality , explaining what chromosome or chromos omal segment is missing or duplicated , and how this may affect the health of the individual carrying the abnormalityNot all wound are prosperous to explain , but some (such as breast cancer colon cancer , type 2 diabetes ) tend to egest more often within acc inflammation inkited families . Using your knowledge of biotechnology , explain how specific DNA abnormalities can be used to determine a mortal`s chances of growing some diseases , and how this knowledge may continue the development of the diseaseANSWERSSingle gene dis may rig out from a mutationSingle gene dis may arise from mutation . The process of transcription and rendition can be disrupted by these forms of mutations . These mutations include virtuoso base telephone exchange that suppress termination of protein translation , alter patterns of mRNA conjoin during transcription (Garden 2002 . Another mutation is bingle base undercut that definitely changes the outcome of mRNA transcription or the protein subtraction of translation . One example of ! a single jail cell dis is the reap hook cell disease . In people with sickle cell disease at least(prenominal) one of the beta haemoglobin subunits in hemoglobin is replaced with hemoglobin S (Genetic Home consultation , 2007 . Sickle red course cells become distorted forming a cell that looks like a sickle .

This distorted red blood cell is uneffective to ripey transfer oxygen and may sometimes encumber up in the blood vessels . The low oxygen might and short life span of sickled red blood cells pillow slips genus Anemia to the person afflicted with these heritable dis . This is a form of single base su bstitution where a normal amino acid (valine ) is replaced by another one (glutamineChromosome abnormality may arise in the offspring of two healthy individualsThree mechanisms contribute to genetic variation during meiosis and bandaging . These are independent miscellany of chromosomes , crossing over and random fertilization . Within these triple processes is window for chromosome dis to occur . Meiotic nondisjunction , the calamity of the chromosomes to disjoin and assume to to opposite poles , in either the initiatory or second meiotic division is the major cause of chromosomal abnormalities (Tissot Kaufman , 2007 . This includes trisomy , which is the mien of 3 chromosomes instead of 2 . fell syndrome , or trisomy 21 , is the classic example of a clement disease caused by autosomal nondisjunction where some , but not all , touched individuals do survive (Tissot Kaufman , 2007 . Trisomy 21...If you want to get a full essay, order it on our website: OrderCustomPaper.com

If you want to get a full essay, visit our page: write my paper